The GIANT consortium currently encompasses 15 study cohorts with 32,387 individuals of European ancestry informative for adult BMI (Supplementary Fig. 1 and Supplementary Table 1). The 15 study cohorts, including between 1,094 and 5,433 individuals each, were genotyped using the Affymetrix 500K Mapping Array Set (11 cohorts, n = 25,394), Illumina HumanHap300 BeadChip (2 cohorts, n = 2,385), Illumina HumanHap300+240 (1 cohort, n = 2,235) or Illumina HumanHap 550 BeadChip (1 cohort, n = 2,265) (Supplementary Tables 2 and 3). To allow for meta-analysis across different marker sets and to improve coverage of the genome, we performed imputation of polymorphic HapMap CEU SNPs (Supplementary Note and Supplementary Table 3) using either MACH (Y. Li, C.J.W., J. Ding, P.S. and G.R.A., unpublished data) or IMPUTE47.
