Expanding our discovery to a meta-analysis of GERA and ICBP also did not indicate significant inflation (average λ=1.042, Supplementary Table 2); this λ is slightly smaller than GERA alone, likely due to the slightly conservative nature of extending the ICBP summary statistics (Online Methods). Thirty-six additional new loci reached genome-wide significance for at least one BP phenotype. Using 152,081 individuals from UKB for replication, 22 loci replicated at P≤0.00067 (Bonferroni for 75 SNPs, see above), 7 were suggestive with P<0.01, and 2 reached nominal significance (P<0.05). As before, all SNPs at least of nominal significance (P<0.05) had the same effect direction in UKB, arguing for a low rate of false positive findings (Figure 4, Supplementary Table 3). We did not detect significant heterogeneity for any lead SNP.
