Finally, to maximize discovery power, we combined all three studies (GERA, ICBP, and UKB, n=321,262). Our genome-wide meta-analysis of SBP, DBP, and PP had λ=1.069, 1.076, and 1.076, respectively. We identified 241 additional novel genome-wide significant loci (Supplementary Figure 6, Supplementary Table 3), although replication was not possible. Only rs139491786 showed heterogeneity evidence (I2=88, P=1.5×10−5).