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Chunk #25 — 3. Results — 3.3. PPI connectivity analysis

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Accumbens functional connectivity during reward mediates sensation-seeking and alcohol use in high-risk youth.
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The whole-brain ANOVA revealed no differences in connectivity by valence but found group differences in NAcc incentive connectivity with midline regions and parietal cortices (FH+>FH−), with a peak cluster centered in the paracentral lobule extending into the precuneus and supplemental motor area, mapping onto the supplementary sensorimotor area (SSMA) (Lim et al., 1994; Penfield and Jasper, 1954). Group differences were also identified in occipital regions (FH−>FH+); see Table 3.