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Chunk #24 — 3. Results — 3.2. Task performance and activation

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Accumbens functional connectivity during reward mediates sensation-seeking and alcohol use in high-risk youth.
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The ANOVA revealed significant effects on extracted task NAcc activation of valence (win>avoid loss; F1,68=70.2, p<0.001) and amount ($5>$0.20; F1,68=60.6, p<0.001), and an interaction between hemisphere and valence (right loss>left loss; F1,68=4.7, p<0.034) but no other interactions (p’s>0.13). See Figure 1 and Table 2 for task results. An additional post-hoc analysis, excluding all subjects with any diagnosis (FH−, n=2; FH+, n=6), confirmed the effect of valence and amount on NAcc activation (both p<0.001) with no significant interactions (p’s>0.14), confirming that subjects with diagnosis were not driving activation results.