In the ‘GTP binding’ category (Table 4), the 7 proteins with higher expression levels in the ACB-shell of ethanol included, hexokinase-1, alpha-tubulin, Ras-related protein Rab-3B, Ac2-048 (Rab1), Atlastin-like protein, Galpha 13, and guanine nucleotide binding protein alpha q polypeptide. None of these proteins were similarly changed by ethanol in the ACB-shell of P or W rats. In addition, none of the 6 proteins in the ‘ATP binding’ category (Table 4) were similarly changed by ethanol treatment in the P or W rats. In the ‘DNA-binding’ category, all 5 histones had higher levels in the ACB-shell of the ethanol-treated NP rats, with 4 of the 5 showing fold changes between 1.30 and 1.38 (Table 3). Histone H1.2 had the smallest increase (1.19-fold) and was the only histone of the 5 that was similarly changed in the W rat.
