has been highlighted in recent GWA reports (Estivill & Armengol, 2007). A survey of the human genome identified more than 3000 CNVs, 800 of which appeared at a frequency of at least 3 percent (Wong, deLeeuw, Dosanjh, Kimm, Cheng et al., 2007). Remarkably, CNVs result in the genomes of individuals differing by as much as 10 million base pairs. Given the speed of discoveries in molecular genetics following from the Human Genome Project, it is likely that many other surprises are in store, which underlines the need for a genome-wide approach.
