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Chunk #9 — Materials and Methods — Subjects

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Independent and Interactive Effects of OPRM1 and DAT1 Polymorphisms on Alcohol Consumption and Subjective Responses in Social Drinkers.
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panel, and urinalysis), and an alcohol breathalyzer test and urine toxicology screen. Recent patterns of alcohol consumption were determined via the 90-day Time Line Follow Back (TLFB) (Sobell and Sobell, 1992) administered by research staff who complete rigorous training and are recertified on the instrument at 6-month intervals. Subjects were excluded from study participation if they met current or lifetime DSM-IV diagnostic criteria for either drug or alcohol abuse or dependence, met current or lifetime DSM-IV diagnostic criteria for any Axis I disorder, had a positive urine drug toxicology test or urine pregnancy test (females) at screening or on test days, or had any ongoing health problems.