Chunk #12 — Materials and Methods — Statistical analyses

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GABRR1 and GABRR2, encoding the GABA-A receptor subunits rho1 and rho2, are associated with alcohol dependence.

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Linkage disequilibrium among genotyped SNPs was evaluated using HAPLOVIEW (Barrett et al., 2005). Coverage of the gene was additionally examined using Tagger (de Bakker et al., 2005) to determine the correlation between genotyped SNPs and all known SNPs in the HapMap I dataset.