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Chunk #6 — Materials and Methods — Sample — Orkney Complex Disease Study (ORCADES)

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Genome-wide association uncovers shared genetic effects among personality traits and mood states.
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This is a family-based, cross-sectional study in the isolated Scottish archipelago of Orkney. Genetic diversity in this population is decreased compared to mainland Scotland (McQuillan et al. 2008). Data from 445 healthy volunteers (57% female) from a subgroup of 10 islands, aged 18–84 years (mean=54.9±13.8) with known Orcadian ancestry, were available. Personality assessments were collected during 2005–2007.