STOCs when the cell was clamped between −100 and 20 mV. Simply considering the driving force at each potential, we can calculate the conductance underlying STOC (G(STOC)) for each event and obtain the relationship between G(STOC) and voltage (Fig. 8 B). Consistent with our observations in gastric smooth muscle cells (ZhuGe et al., 2002), G(STOC) increased as the voltage became less negative. We further analyzed the relationship between STOC τdecay and voltage and between TTODSTOC and voltage. Interestingly, STOC τdecay increased as the voltage became less negative, but the TTODSTOC was flat across the voltages examined in ASM cells (Fig. 8, B and C).
