The Influenza Genome Sequencing Project (IGSP) (34) is providing researchers with a growing collection of over 40 000 virus sequences essential to the identification of the genetic determinants of influenza pathogenicity. NCBI’s Influenza Virus Resource links the IGSP project data via PubMed to the most recent scientific literature on influenza as well as to a number of online analysis tools and databases. These databases include NCBI’s Influenza Virus Sequence Database, comprised of over 70 000 influenza sequences in the GenBank and RefSeq databases, as well as other Entrez databases containing 113 000 influenza protein sequences, 140 influenza protein structures and 490 influenza population studies. An online influenza genome annotation tool analyzes a novel sequence and produces output in a ‘feature table’ format that can be used by NCBI’s GenBank submission tools such as tbl2asn (1).
