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Chunk #24 — RESULTS — Analysis of the full sample

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Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans.
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CHRNB1 is represented in Table 3 by rs7210231 and rs2302761, which are highly correlated in our EA sample (r2 = 0.99) but somewhat less so in AAs (r2 = 0.61). Rs7210231 shows greater consistency across populations (in EAs only, OR=0.80 (0.69-0.94), p=0.0052; in AAs only, OR = 0.79 (0.62-1.02), p = 0.065)