Chunk #24 — Online methods — Lung cancer susceptibility variants in other phenotypes — Lung function

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Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

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The lung function in silico look up was conducted in SpiroMeta consortium, which included 38,199 European ancestry individuals. The genome-wide associations between genetic variants and forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC) and FEV1/FVC with 1000 Genomes Project (phase 1)-imputed genotypes in the GWAS with 38,199 individuals36.