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Chunk #29 — Results — Use of Ancestry Informative Markers for Admixture Studies

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Ancestry informative marker sets for determining continental origin and admixture proportions in common populations in America.
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Another major use of continental AIMs is in admixture studies. The differences in admixture proportions estimated using the 128 In4 AIMs is illustrated in Fig. 1 and summarized in Table 2 for African Americans (AFA), Mexican Americans (MAM), Mexican (MXN) and Puerto Rican (PRA) population groups. These results using STRUCTURE, similar to those with continental populations, are robust and yield consistent admixture proportions in multiple runs using appropriate analysis parameters (see Methods). The results also show that the overall admixture proportions of these groups, AFA, MAM, MXN and PRA can be ascertained with small numbers of In4 AIMs.