MRPS33P4, ADCY9), two loci for obesity class II (HS6ST3, ZZZ3), and one locus associated with both overweight and obesity class I (HNF4G) (Table 1, Supplementary Fig. 5-7). Although these loci were identified for specific clinical classes of obesity, all novel loci showed consistent effect direction across the tails of BMI and the other class of obesity, and most P-values were significant (P<0.007, Bonferroni-corrected for 7 SNPs), except for obesity class III and the tails of BMI (presumably due to lower statistical power for these traits; Table 2).
