National surveys on alcohol use statistics and Alcohol Use Disorder (AUD) studies show that only one-third of individuals with AUD attempted to quit drinking every year1. Of them, only 25% were successful in reducing alcohol consumption for more than a year1. At the same time, there are ongoing debates over courts and correctional programs admitting individuals into rehabilitation programs given their efficacy and program’s outcome2,3. Therefore, it is of great importance to be able to identify AUD resilience and readiness to recover features including predisposition characteristics that can predict a change in drinking behavior, consequently impacting therapeutic approaches to AUD, helping individuals overcome addiction and overall reducing state, and federal associated financial burden. Few studies have investigated the characteristics of those with AUD who reduce alcohol consumption, but they have often focused on psychosocial aspects3 and initial consumption measurements4,5, leaving physiological and genetic variables unexplored.
