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Chunk #24 — Discussion

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Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.
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EHR-based studies offer additional benefits. Our identification of new variants takes advantage of multiple independent measurements in the EHR to increase statistical power7. Our study increased the standardization and reduced the variability of the EHR-derived BP measures by excluding measures obtained in clinical settings with increased measurement variability, e.g., emergency rooms, retaining measures obtained in visits to primary care/Internal Medicine departments.