Here we investigated gene expression in peripheral blood from 1,469 individuals to identify cis- and trans-effects of common variants on gene expression levels. When comparing to other genetical genomics studies [12]–[14], [16], [18], [21]–[24], [45], [46] we observe an increasing percentage of genes that are cis- or trans-regulated (39% of 19,689 unique genes at FDR 0.05). When eQTL studies further increase the sample-sizes and thus increase statistical power, we expect that for the far majority of genes the expression levels are to some extent determined by genetic variation.