Analyses of the craving scale revealed a significant effect for abstinence, F(2,194) = 30.24, P < 0.0001, indicating that craving increased significantly after abstinence. Analysis of the CNR1 SNP revealed a significant main effect, F(2,194) = 4.3, P < 0.041, but no interaction, indicating that craving was significantly greater at pre-abstinence, post-abstinence and post-cue exposure from marijuana for the CNR1 T/C group (see Fig. 5). Analysis of the FAAH SNP revealed a significant abstinence × genotype interaction, F(2,194) = 3.90, P < 0.04, but no significant main effect for the FAAH SNP. The FAAH C/C group demonstrated a greater increase in craving after abstinence compared to the FAAH C/A group (see Fig. 6). Exposure to the marijuana cues did not impact significantly any of the mood scales.
