Chunk #20 — RESULTS — Association of rs13273442 in European and African Ancestry Samples

Source

Multiple distinct CHRNB3-CHRNA6 variants are genetic risk factors for nicotine dependence in African Americans and European Americans.

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Meta-analyzing the 6 race-by-study strata (Table 2) tightened the confidence interval for the estimated nicotine dependence odds ratio of 0.77, corresponding to an improvement in the p-value to 8.6 × 10−5.