Among HR offspring, level of prenatal alcohol exposure was significantly associated with offspring SUD outcomes after controlling for SES, gender, prenatal cigarette exposure, and prenatal exposure to other drugs (Wald=5.54, p=.019) (Figure 6). Prenatal alcohol exposure influenced both alcohol use disorders (Wald=8.61, p=.003) and drug use disorders (Wald=4.52, p=.03). However, prenatal alcohol exposure was not associated with offspring cigarette use, and no covariates were significantly associated with offspring substance use outcomes.