Offspring cigarette use, but not substance use disorder, was influenced by prenatal use of cigarettes after controlling for SES, gender, prenatal alcohol or other drug exposure (Wald=8.04, p=.005) (Tables 3b & 4b). Cigarette-exposed offspring had higher rates and earlier ages of cigarette use (Figure 5). Prenatal alcohol exposure was the only significant covariate (Wald=4.74, p=0.029). Analyses were repeated excluding the offspring of three low-risk mothers who had previously met criteria for SUD. The significance of results remained consistent.