The changes in splice junctions could explain most exon and intron changes in alcoholic brains. Splice junctions increased at exons 6-7 and exons 7-8, and they potentially altered expression of neighboring exons 7 and 8 explaining why their expression increased. Splice junctions decreased at exons 9-10 and exons 10-11 indicating that exon 10 spliced in transcripts were less abundant in alcoholic brains. The increase in splice junctions at exons 11-12 may explain why their expression increased. Splice junctions increased at exons 13-14 suggesting expression increase of transcripts containing exon 14. Lastly, splice junctions increased at exons 15-16 and deceased at exons 16-17 indicating specific expression increases in transcripts containing exon 15 and 16 (Figure 7).
