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Chunk #43 — Discussion

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Absence of P300 reduction in South African treatment-naïve adolescents with alcohol dependence.
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yes

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Some degree of caution in interpreting the results is warranted given the limited sample sizes of the current study, especially with regards to adolescent TNAD males (n = 15). Nonetheless, the P3b amplitude results for this sample of TNAD males are very supportive of our interpretations that P3b amplitude is not reduced in the AUD population studied. The P3b amplitudes are 22% (although not statistically significantly) larger in the TNAD group than the NSAC group. Longitudinal follow-up of samples such as those studied here could elucidate the stability of the findings over time with continued exposure to hazardous drinking.