Chunk #35 — DISCUSSION

Source

Novel common copy number variation for early onset extreme obesity on chromosome 11q11 identified by a genome-wide analysis.

Embedded

yes

Text

In summary, we provide evidence for a new common CNVR for early-onset (extreme) obesity on chromosome 11q11 covering the coding regions of OLR genes. Moreover, we confirmed two previously described common CNVRs for obesity. Overall, however, common CNVRs seem to be of minor importance to account for the ‘missing heritability’ of early-onset (extreme) obesity.