While the data presented here are sparse, they do collectively form a cohesive argument that glucocorticoids can promote endocannabinoid signalling through a non-genomic pathway to exert rapid behavioural changes. The role of endocannabinoids in other rapid behavioural effects of glucocorticoids such changes in aggressive behaviour (Mikics et al., 2004) and risk assessment (Mikics et al., 2005) should also be investigated to determine if endocannabinoid signalling is a broad mediator of the rapid behavioural effects of glucocorticoids.
