RNA-seq based transcriptome data were generated from post-mortem brain tissue collected from cerebellum (CB; 189 samples) and temporal cortex (TC; 191 samples) of Caucasian subjects [18, 38]. RNA was extracted using Trizol® reagent and cleaned with Qiagen RNeasy. RIN measurement was performed with Agilent Technologies 2100 Bioanalyzer. Samples with RIN > 5 were included. Library was prepared by Mayo Clinic Medical Genome Facility Gene Expression and Sequencing Cores with TruSeq RNA Sample Prep Kit (Illumina).
