These four SNPs (rs1650420, rs6497730, rs4587976 and rs1070487) are common in both AA and EA (MAF > 0.33, Table 4), but the minor allele frequencies differ between these ethnic groups. The four SNPs are more common in EA and the difference in allele frequency of rs1650420 is significant after correction for multiple testing (P = 3.5E-06, Table 4). The minor alleles of SNPs rs1650420, rs1070487 and rs6497730 in AA are the major alleles in EA (Table 4).
