Phenotype WGs consist of representatives from each study contributing data to that phenotype's cross-study analyses. These representatives generally have expertise in the subject area and are aware of the intricacies involved in categorizing or characterizing the phenotype. The WGs also have representatives from the NIH and the CC. Each WG is led by an investigator with a specific interest in the phenotype who manages and coordinates the group's activities. The WGs evaluate the feasibility and logistics for cross-study analyses related to specific phenotypes of interest. They identify and define variables to be shared, identify covariates, recommend the most appropriate analytic methods, draft analysis plans using a template developed by the PHS, and identify the investigators performing the analyses, usually members of the WG.
