The CC is responsible for phenotype data organization and coordinating activities related to data collection and management and facilitating cross-study analyses. The CC assists the PHS with identifying potential areas of common interest, harmonizes covariates, and establishes and manages a centralized relational database which serves as a common phenotype/genotype repository providing working groups with cross-study data upon request. The CC assists working groups with phenotype harmonization and provides them with statistical summaries of phenotype data and a central file-sharing site. The CC may also assist working group investigators with data analysis, if requested.