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Chunk #9 — DIMENSIONS OF PSYCHOPATHOLOGY IN NEUROLEPTIC-NAÏVE PATIENTS WITH RECENT-ONSET SCHIZOPHRENIA

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Fronto-temporal dysfunction in schizophrenia: A selective review.
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and Kaiser normalization. Three components with eigen value>1 were extracted, viz., negative (affective flattening, alogia, avolition, anhedonia, and inappropriate affect), psychosis (delusions and hallucinations), and disorganization (positive formal thought disorder and bizarre behavior). Cumulatively, these three dimensions with eigen values > 1explained 74.07% of the variance in psychopathology. The results of the study suggest that the three dimensions of schizophrenia psychopathology, viz., positive, negative, and disorganization are valid even in neuroleptic-naïve, recent-onset patients with schizophrenia/schizophreniform disorder. However, it must be borne in mind that the sample size of the study was modest and the entire spectrum of symptoms found in schizophrenia was not explored (e.g. affective symptoms, anxiety symptoms, arousal symptoms, etc.).