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Chunk #24 — 3. Results — 3.2. Effects of ethanol on protein levels in NP rats

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Differential effects of ethanol in the nucleus accumbens shell of alcohol-preferring (P), alcohol-non-preferring (NP) and Wistar rats: a proteomics study.
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Only 7 of the 128 proteins that were altered by ethanol treatment in the ACB-shell of the NP rats were similarly changed in the ACB-shell of P and W rats (Tables 2, 3 and 5); there was 1 protein (19 kDa protein) that was changed in the opposite direction in NP versus W rats. There were no proteins that were significantly changed in the opposite direction by ethanol in the ACB-shell of NP versus P rats. Therefore, ethanol appeared to produce unique changes in protein expression in the ACB-shell of NP rats that were not observed in P or W rats.