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Chunk #18 — Results — Genetic correlation of stimulant dependence with other psychiatric disorders

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Genome-wide association study of stimulant dependence.
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for stimulant dependence and ADHD in both AAs (adjusted p = 3.0 × 10−33) and EAs (adjusted p = 6.7 × 10−35), no individual variants showed significant pleiotropic effects on stimulant dependence and any of the other disorders after multiple testing correction.Table 3Genetic correlation (rg) and pleiotropy between stimulant dependence and other psychiatric disorders by population group.TraitAfrican AmericanEuropean AncestryrgCorrelation p-valuePleiotropy padjrgCorrelation p-valuePleiotropy padjAlcohol dependence0.118.0E−161.1E−010.207.2E−553.6E−03ADHD0.0533.5E−053.0E−330.101.5E−146.7E−35Anxiety0.0339.2E−038.9E−01−0.0028.8E−012.1E−04