We used an a priori anatomic template to define the network nodes used in our analyses. This approach is widely used in the literature (19,38,39), but the node definitions remain arbitrary. Further work examining the effects of template selection on reported findings will be important to determine their generalizability (79–81). In addition, our analyses suggested that antipsychotics could not account for our case–control differences, although more systematic investigation of medication effects on functional connectivity is required given emerging evidence that connectivity can be modulated by antipsychotic use (82,83).
