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Chunk #23 — Results — Polygenic Scores

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Clinical, genomic, and neurophysiological correlates of lifetime suicide attempts among individuals with alcohol dependence.
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Figure 1, Panel A presents the meta-analyzed results for associations between each of the corresponding PGSs and lifetime suicide attempt within those meeting criteria for AD. PGSs for DEP (ORMETA = 1.34, 95% CI = 1.18, 1.53), PTSD (ORMETA = 1.23, 95% CI = 1.03, 1.45), and SUI (ORMETA = 1.44, 95% CI = 1.22, 1.70) were associated with increased odds of reporting suicide attempt. However, the AUD, BIP, SCZ, and SMOK PGSs were not associated with suicide attempt (ancestry-specific results in Table S8).