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Chunk #10 — MATERIALS AND METHODS — SAGE Data

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Convergence of genome-wide association and candidate gene studies for alcoholism.
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The power Calculator for Association with Two Stage design (CATS) was used to determine what effect sizes the SAGE dataset is able to detect (Skol et al., 2006). Using a sample size of 1900 cases and 1900 controls and an alpha level of .05, we calculated different allele frequencies and risk ratios.