Chunk #26 — Materials and Methods — STATISTICAL ANALYSES — — Analysis of genetic association

Source

Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies.

Embedded

yes

Text

We also examined STAR*D and meta-analysis results for SNPs within 50 kb of forty-one previously-noted MDD candidate genes. For the meta-analysis, we used a permutation-based procedure to determine whether the distribution of P-values observed for these SNPs deviated from chance expectation (see Supplementary Methods for details)