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Chunk #100 — 3 Neuropeptide Roles in Acute and Chronic Alcohol Actions — 3.1 Corticotropin-Releasing Factor — 3.1.2 Corticotropin-Releasing Factor Actions in the Central Amygdala

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Synaptic effects induced by alcohol.
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yes

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The central amygdala (CeA) contains CRF receptors and abundant CRF-containing fibers (De Souza et al. 1984) (Uryu et al. 1992); CRF itself is generally co-localized in CeA neurons together with GABA (Eliava et al. 2003) (Asan et al. 2005). Acute EtOH augments evoked GABAA receptor-mediated inhibitory postsynaptic currents (IPSCs) by increasing GABA release in both mouse (Bajo et al. 2008; Nie et al. 2004) and rat CeA neurons (Roberto et al. 2003, 2004).