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Chunk #40 — DISCUSSION

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The effects of age at drinking onset and stressful life events on alcohol use in adulthood: a replication and extension using a population-based twin sample.
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A number of methodological differences between our measures and analytic approaches may partially explain the differences in results. Dawson and colleagues (2007) reported the interaction finding in terms of the effect on average daily drinking associated with each additional stressful event. After adjusting for demographic characteristics, the per-stressor effect on daily drinking was 16% higher among those with young drinking onset (ages ≤14), and 7% among those with middle drinking onset (ages 15 to 17) compared with those with older drinking onset. We used a different measure of drinking outcome that reflected typical and heavy drinking days and only analyzed stressful events of moderate or severe intensity, so our effects sizes are not directly comparable. We found that after adjusting for demographic covariates, the effect on past-year drinking associated with each SLE (up to 3) among individuals with young onset was 138% (1.2 drinks/wk) higher for women and 99% (2.7 drinks/wk) higher for men, compared to those with older onset. Among those with middle onset, PYDD was found to be 55% (0.5 drinks/wk) higher among women and 70% (1.3 drinks/wk)