The Framingham Offspring Study is a prospective cohort study that recruited 5,124 individuals beginning in 1971 (Feinleib et al., 1975). We identified 2,177 young adults aged 18 to 40 years with available data on BMI. BMI was assessed at baseline and during six subsequent visits to ascertain incident severe obesity. Individuals with severe obesity at baseline or missing data from subsequent visits were excluded.
