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Chunk #13 — II. Materials and Methods — Measures used in the SEM

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Testing a level of response to alcohol-based model of heavy drinking and alcohol problems in 1,905 17-year-olds.
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drinks for effects actually experienced during that early drinking phase (Schuckit et al., 1997). The SRE has a one-year retest reliability of .82, a Cronbach α of > .90, and overlaps at about .60 with another LR measure (the alcohol challenge) regarding the ability of LR to predict future drinking patterns and problems (Schuckit et al., 1997, 2009b; Ray et al., 2007). In the SRE, a greater number of drinks required for effects indicates a lower response per drink, or a lower LR as would be measured on alcohol challenges (Schuckit et al., 2001, 2010). SRE scores are generated by summing the number of drinks required across effects, and dividing that figure by the number of effects reported. Alcohol challenge and SRE-based LR's perform similarly when used to identify higher and lower LR subjects who are then evaluated in functional brain imaging, and when results from the two measures are compared in similar structural equation model (SEM) approaches (Schuckit et al., 2010).