The LR to alcohol, a manifest variable in the SEM, was evaluated using the Self-Rating of the Effects of Alcohol (SRE) Questionnaire where subjects retrospectively reported the number of U.K. standard units of drinks (8 g of ethanol) they estimated had been required for each of up to four effects the approximate first five times of drinking (Schuckit et al., 2009b). All subjects who consumed ≥ 1 drink were asked to make their best estimates, but to only give estimates for effects they actually experienced in the noted time frame. The SRE includes the amount of alcohol required to begin to feel the first effects, the drinks needed to begin to feel slurring of speech, the alcohol needed to produce a stumbling gait, and the drinks required for unwanted falling asleep, with subjects instructed to only report the number of drinks for effects actually experienced during that early drinking phase (Schuckit et al., 1997). The SRE has a one-year retest reliability of .82, a Cronbach α of > .90, and overlaps at about .60 with another LR measure (the alcohol