Following guidelines of the relevant Law Ethics Committee and the Local Research Ethics Committee, as described in detail elsewhere, ALSPAC is a study that began in 1991 to prospectively follow a birth cohort attempting to enroll all singleton children born to 14,541 pregnant women in Avon, England between 4/1/1991 and 12/31/1992 (Golding et al., 2001). Self-administered questionnaires were regularly used to gather data from the mothers during the pregnancy and the early developmental period of the offspring. Among these subjects, a subset of about 8,000 children continued with face-to-face evaluations every 18 months beginning at age seven. The current data are based on the first of 1,905 males and females (44.2% male) who had consumed at least one full drink and who participated in personal interviews in the age 17+ assessment clinic. The large majority (98.2%) of the participants were Anglo-European, with the remainder comprised of individuals with Pakistani/Indian, Chinese, and Caribbean ancestry.
