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Chunk #27 — Results — Power

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Polygenic Risk Score Prediction of Alcohol Dependence Symptoms Across Population-Based and Clinically Ascertained Samples.
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Table 4 presents calculations of the expected power each validation sample had to detect associations for polygenic scores accounting for 0.2% to 5% of the phenotypic variance. All samples had adequate power to detect associations accounting for 2% or more of the trait variance, which is comparable to or less than what others have found using the same genome-wide polygenic risk scoring method (The International Schizophrenia Consortium, 2009; Salvatore et al., 2014; Hart and Kranzler, 2015).