While determining the isoforms and full structures of all lincRNAs is clearly desirable, these incomplete lincRNA structure annotations are nonetheless of tremendous practical value. Knowledge of the structure of a portion of a transcript is often sufficient to test for differential expression or perform RNAi knockdown experiments, and facilitates the cloning and sequencing of the full length transcript. Because of this, instead of placing additional restrictions upon lincRNA annotations, our filtering strategy was aimed toward identification of as many transcripts as possible that fit within the definition of a lincRNA. However, for investigators interested in more refined lincRNA annotations, we have provided multiple more restrictive lincRNA catalogs (Datasets S4, S5, S6).
