Externalizing has been consistently linked to suicide related outcomes at the phenotypic20,63–65 and genetic level16,20,21,66,67, pointing to the importance of behavioral disinhibition and impulsivity in suicidality. In the current analysis, we sought to characterize how genetic liability for externalizing is related to suicide outcomes within the veteran population using the VA’s Million Veteran Program Cohort to further explore this overlap, using genetic data from European-like and African-like populations. We were able to recapitulate a latent externalizing factor that overlapped strongly with prior results (rg = .87) which contained no MVP data16. Additionally, we expanded prospective analyses for externalizing and mortality into the full MVP sample.
