No effect of LPS was observed during the initial period of sucrose consumption or after first deprivation (from sucrose) (one week). After the second deprivation (one month), a slight reduction in preference for sucrose in LPS pretreated B6 male mice was found. Females did not change the preference for sucrose in any of the periods of measurement. Complete data for intake of different tastants (preference for saccharin, quinine, and sucrose, as well as total fluid intake) in a continuous-access, two-bottle choice test are presented in Supplemental Figs. 13–18 (for detailed statistics see Supplementary materials in Supplemental Table 5). Increased alcohol consumption could be produced by increased perception of sweet taste or decreased perception of bitter taste, but such changes in taste perception do not appear to result from LPS treatments.
