The preference for bitter solutions of quinine was increased (reduced avoidance) in B6 male mice during the initial period of measurement. Post-hoc analyses showed significant differences between saline- and LPS-pretreated groups for concentration of quinine 0.06 mM. A small reduction in preference for quinine in B6 male mice was observed also after the second (one-month) period of deprivation (from quinine). No differences were found after the first (one-week) period of deprivation. Females of the B6 inbred strain did not show any differences in preference for quinine during the initial period of measurement. However, after deprivation a slight reduction (increased avoidance) in preference for quinine in LPS pretreated animals was found.
