We attempted to replicate findings for our top SNP by genotyping it in 1822 elderly white participants from the 3C-Dijon study18,19 and 644 African American participants from the ARIC study.10 We also 59 explored SNPs within 300kb of our top SNP using in-silico replication in the African American sample (Appendix, Section 7).10 We set the threshold for replication at a one-sided p-value of 0.05.
